ncRNA name | hsa-miR-150 |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human umbilical vein endothelial cells (HUVECs) |
Methods | Western blot, qPCR |
Expression pattern | down-regulated |
Functional description | Deletion of miR-150 significantly increased the retinal pathological angiogenesis in HFD induced type 2 diabetic mice. Overexpression of miR-150 in cultured endothelial cells caused a significant reduction of vascular endothelial growth factor receptor 2 (VEGFR2) protein levels. |
PubMed ID | 27304911 |
Year | 2016 |
Title | Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice. |
Drug-related ncRNA | NO |
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